Use of Poly(3‑hydroxybutyrate) as Polymer Base for Drug Delivery Systems

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F20%3APU137957" target="_blank" >RIV/00216305:26310/20:PU137957 - isvavai.cz</a>
Result on the web
<a href="https://www.fch.vut.cz/vav/konference/sok/vystupy/sbornik-abstrakty-konference-2020-pdf-p198641" target="_blank" >https://www.fch.vut.cz/vav/konference/sok/vystupy/sbornik-abstrakty-konference-2020-pdf-p198641</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Use of Poly(3‑hydroxybutyrate) as Polymer Base for Drug Delivery Systems
Original language description
One of the most discussed applications of polyhydroxyalkanoates (PHA) is their use in medicine as scaffolds, drug carrier systems, and wound dressings, made by solution casting, electrospinning, or thermoplastic extrusion. Often, the porosity was found as an essential attribute of specimens used for pharmaceutical and medical applications. the PHA porous materials offer unique properties such as biocompatibility, bioactivity, non‑cytotoxicity, and biodegradability. This contribution is focused on the study of the release of active substances from porous structures based on poly(3‑hydroxybutyrate) (PHB) films. PHB is a semicrystalline biopolyester with the ability to degrade in vivo and in vitro without toxic substances. The porous scaffolds were formed from PHB by electrospinning. This work confirmed that the morphology of PHB scaffold is possible to varied by the PHB concentration and solvents used for electrospinning. Scanning electron microscopy revealed the formation of different morphologies, inc
Czech name
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Czech description
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Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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