Characterization of albumin and hyaluronan‑albumin mixed hydrogels
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F21%3APU141530" target="_blank" >RIV/00216305:26310/21:PU141530 - isvavai.cz</a>
Result on the web
<a href="https://link.springer.com/article/10.1007/s11696-021-01853-y" target="_blank" >https://link.springer.com/article/10.1007/s11696-021-01853-y</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s11696-021-01853-y" target="_blank" >10.1007/s11696-021-01853-y</a>
Alternative languages
Result language
angličtina
Original language name
Characterization of albumin and hyaluronan‑albumin mixed hydrogels
Original language description
Various hydrogels prepared from natural polymers have found great use in different industries, including, but not limited to, biomedicine. Recent trends in the material development focus on the preparation of hydrogels based on two or more biopolymers to combine their properties, which leads to better performance of a resulting material. In the present work, albumin and mixed hyaluronan-albumin hydrogels were characterized using various methods. The rheological properties of the samples varied based on the sample composition. The addition of hyaluronan to the albumin samples lowered the crosslink density of the hydrogels resulting in the lower complex modulus values and the higher equilibrium swelling ratio. Increasing the ionic strength of the sample shifted the albumin denaturation temperature of the water solutions to higher temperatures and suppressed the effect of hyaluronan on the denaturation. Scanning electron microscopy images showed that the microstructure of albumin samples significantly differs from the structure of mixed hyaluronan-albumin samples. The release profiles of a reference dye (methylene blue) showed, that the diffusion of the dye was rather slow. The released amounts of a dye from hydrogel into the buffer (physiological conditions model) varied from 6.35 ± 0.35% up to 9.78 ± 1.42% (after 96 h).
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10403 - Physical chemistry
Result continuities
Project
—
Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Chemical Papers
ISSN
0366-6352
e-ISSN
1336-9075
Volume of the periodical
75
Issue of the periodical within the volume
11
Country of publishing house
SK - SLOVAKIA
Number of pages
8
Pages from-to
1-8
UT code for WoS article
000692988600003
EID of the result in the Scopus database
2-s2.0-85114313363