Study of cholesterol’s effect on the properties of catanionic vesicular systems

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F21%3APU141581" target="_blank" >RIV/00216305:26310/21:PU141581 - isvavai.cz</a>
Alternative codes found
RIV/00216305:26310/20:PU138776
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Study of cholesterol’s effect on the properties of catanionic vesicular systems
Original language description
This work is focused on the study of properties and stability catanionic vesicles at laboratory temperature. Catanionic vesicles were based on the ion pair amphiphile (IPA), which was prepared by mixing equivalent volumes of aqueous solution HTMAB (hexadecyltrimethylammonium bromide) and SDS (sodium dodecylsulphate). Then the precipitate was obtained and after removal of the counterions of these surfactants, IPA was formed. The residue IPA was denoted as HTMA-DS. To improve stability positively charged double-chained dioctadecyldimethylammonium chloride (DODAC) and cholesterol were added. The total amount of cholesterol was set to 0, 3, 13, 23, 33, 43, 53, 63 and 73 mol.%. In this system, the size distribution was studied using the dynamic light-scattering (DLS) and zeta potential was determined by electrophoretic light-scattering. These standard techniques were supplemented by fluorescence spectroscopy technique. Specifically, generalized polarization (GP) was measured using a Laurdan probe. This pro
Czech name
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Czech description
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Project
<a href="/en/project/GC19-14024J" target="_blank" >GC19-14024J: Hyaluronan-catanionic vesicles complexes – interaction, structure, physical property, and stability</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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