Structural and Mechanical Analyses of Hydrogel Systems Modified by Lecithin Nanodomains

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F21%3APU141893" target="_blank" >RIV/00216305:26310/21:PU141893 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Structural and Mechanical Analyses of Hydrogel Systems Modified by Lecithin Nanodomains
Original language description
Design of the hydrogels with the tunable properties capable to imitate native extracellular matrix (ECM) is widely discussed topic in recent years. With respect to faithful imitation of ECM, this proposed study mostly utilizes biocompatible and biodegradable materials with ability to form crosslinked 3D networks (hydrogels) with further potential use as barrier materials, drug carrier in regenerative medicine, tissue engineering, etc. The inner structure (related to viscoelastic and transport properties) of the basic 3D matrix material were modified by phospholipid lecithin, which in water-based solutions forms organized nanodomain structures and consequently affects the final structural properties of the prepared hydrogels. These structural modifications then consequently lead to distinct mechanical properties. Hydrogel systems, physically, chemically, and ionically crosslinked, were subjected to the structural characterization in the dried form of xerogel using direct visualization technique (scann
Czech name
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Czech description
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Project
<a href="/en/project/EF19_073%2F0016948" target="_blank" >EF19_073/0016948: Quality internal grants at BUT</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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