The role of polyhydroxyalkanoates in adaptation process of Cupriavidus necator under stress conditions

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F22%3APU144403" target="_blank" >RIV/00216305:26310/22:PU144403 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

The role of polyhydroxyalkanoates in adaptation process of Cupriavidus necator under stress conditions

Original language description

Application of approaches of evolutionary engineering could be used to obtain microorganisms producing PHAs with required properties. Method is useful, quite simple and effective for gaining microbial strains with suitable characteristics on phenotype level (e.g. more effective growth, better productivity, ability of utilization different sources of carbon etc.) with no requirement for knowledge of genetic characteristics of original wild-type strain. Polyhydroxyalkanoates (PHAs) are microbial polymers which could replace traditional petrochemical plastics due to their favorable properties such as biodegradability and biocompatibility. Moreover, properties of PHAs depend on monomer composition, therefore materials for selected purpose could be produced, e.g. by application of evolutionary engineering tools od PHAs producing microorganisms. Considering evolutionary engineering, PHA can take a role in adaptation process due to generally enhanced robustness of PHA accumulating bacterial cells against str

Czech name

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Czech description

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Type

O - Miscellaneous

CEP classification

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OECD FORD branch

20903 - Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials

Project

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Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2022

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů