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Tailoring the internal microstructue of the hydrogels based on poly-HEMA targeted for drug delivery systems

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F22%3APU145860" target="_blank" >RIV/00216305:26310/22:PU145860 - isvavai.cz</a>

  • Result on the web

    <a href="https://www.confer.cz/nanocon/2021/4350-tailoring-the-internal-microstructure-of-the-hydrogels-based-on-poly-hema-targeted-for-drug-delivery-systems" target="_blank" >https://www.confer.cz/nanocon/2021/4350-tailoring-the-internal-microstructure-of-the-hydrogels-based-on-poly-hema-targeted-for-drug-delivery-systems</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.37904/nanocon.2021.4350" target="_blank" >10.37904/nanocon.2021.4350</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Tailoring the internal microstructue of the hydrogels based on poly-HEMA targeted for drug delivery systems

  • Original language description

    The transport and barrier properties are important material characteristics in terms of the development of the targeted drug delivery systems. Therefore, this work focused on the study of the possibility of influencing these properties and internal architecture in a model hydrogel system formed by a semi-interpenetrating polymer network with an incorporated polyelectrolyte component. Due to its application potential and its extensive use in medicine, poly(2-hydroxyethyl methacrylate) was chosen as the model hydrogel system for this work. Sodium polystyrene sulfonate was used as the interpenetrating linear polymer. Scanning electron microscopy was used to examine the structure of the three-dimensional hydrogel network. Transport properties were monitored by diffusion tests. Furthermore, diffusion through the hydrogel (barrier properties) was monitored using diffusion cells (Franz cells, horizontal cells). The usability of the semi-interpenetrating polymer network concept for the preparation of materials with tunable relevant properties was confirmed on the proposed materials.

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

  • OECD FORD branch

    10403 - Physical chemistry

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2022

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    CONFERENCE PROCEEDINGS - NANOCON 2021

  • ISBN

    978-80-88365-00-6

  • ISSN

  • e-ISSN

  • Number of pages

    6

  • Pages from-to

    280-285

  • Publisher name

    TANGER Ltd.

  • Place of publication

    Ostrava

  • Event location

    Brno

  • Event date

    Oct 20, 2021

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article