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ČeštinaEnglish

Selenium containing heterocyclic: Synthesis, antimicrobial of some new selenazole Substituted phthalazin-ones

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F13%3APU108211" target="_blank" >RIV/00216305:26620/13:PU108211 - isvavai.cz</a>

  • Result on the web

    —

  • DOI - Digital Object Identifier

    —

Alternative languages

  • Result language

    angličtina

  • Original language name

    Selenium containing heterocyclic: Synthesis, antimicrobial of some new selenazole Substituted phthalazin-ones

  • Original language description

    The principal purpose of the present study is to synthesize and investigate the antimicrobial and antifungal activities of new 1, 3-selenazole derivatives having phthalazin-1(2H)-one moieties. A multi-step reaction route was developed to synthesize a several of targeted derivatives starting from 4-alkyl/aryl-phthalazin-1(2H)-one and 2-chloro-N-phenylacetamide. The structures of the synthesized compounds were confirmed by 1HNMR, 13CNMR, MS, IR spectroscopy and by elemental analysis. The antimicrobial andantifungal activities of all derivatives against four species of bacteria and two species of fungi were investigated. The antimicrobial and antifungal activity was determined in the extracts using disk diffusion method. Amoxicillin and Ketoconazole wereused as standard drugs for the bacteria and fungi, respectively.

  • Czech name

    —

  • Czech description

    —

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    JU - Aeronautics, aerodynamics, aeroplanes

  • OECD FORD branch

    —

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2013

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Life Science Journal

  • ISSN

    1097-8135

  • e-ISSN

    —

  • Volume of the periodical

    10

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    CN - CHINA

  • Number of pages

    11

  • Pages from-to

    799-809

  • UT code for WoS article

    —

  • EID of the result in the Scopus database

    —

Similar results(10)

Synthesis and Antimicrobial Evaluation of Some New 2-(5,6-Dihydro-4H-1,2,4- triazolo[4,3-a]benz[F]azepin-1-yl)methyl)-4-substituted Phthalazin-1(2H)-onesSelenium containing heterocycles: Synthesis and antimicrobial evaluation of some new 4-substituted-2-(4- phenyl-2-(piperidin-1-yl)-1, 3-selenazol-5-yl) phthalazin-1(2H)-onesSynthesis of Some Biologically Active Pyrazolylphthalazine Derivatives and Acyclo-C-nucleosides of 6-(2,4,6-trimethylphenyl)-1,2,4-triazolo[3,4-a]phthalazine