Novel hydrogels based on natural polysaccharide Gum Karaya for soft tissue regeneration

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F15%3APU115087" target="_blank" >RIV/00216305:26620/15:PU115087 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Novel hydrogels based on natural polysaccharide Gum Karaya for soft tissue regeneration

Original language description

Natural polysaccharides are biodegradable, freely available, relatively cheap and nontoxic materials. They are widely used in food and pharmaceutical industry. Moreover, polysaccharide based hydrogels are promising for use in medicine. They provide moistenvironment which stimulates faster wound healing. Hydrogels can be utilized as wound dressing for soft tissue regeneration (e.g. skin burns or ulcers). Gum Karaya (GK) is a natural polysaccharide obtained from Sterculia urens tree. GK is anionic polysaccharide containing ?-D-galactose, L-rhamnose, ?-D-glucuronic acid and Dgalacturonic acid. Natural GK is partially acetylated high molecular weight polymer (Mw ? 9 mil Da) insoluble in water. On the other hand, GK is biodegradable and cheap having high swelling and retention capacity, high viscosity and inherent antimicrobial activity. Therefore, GK has good potential to be utilized in medicine. [1, 2] The objective of this study is preparation a soluble sample of GK by alkali treatment

Czech name

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Czech description

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Type

O - Miscellaneous

CEP classification

CD - Macromolecular chemistry

OECD FORD branch

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Project

<a href="/en/project/ED1.1.00%2F02.0068" target="_blank" >ED1.1.00/02.0068: Central european institute of technology</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů