Combination of X-ray micro-Computed tomography and laser-ablation based analytical techniques for 3D high resolution elemental mapping
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F16%3APU121351" target="_blank" >RIV/00216305:26620/16:PU121351 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Combination of X-ray micro-Computed tomography and laser-ablation based analytical techniques for 3D high resolution elemental mapping
Original language description
Detection and chemical 3D mapping of nanoparticles (NPs) distribution in biospecimen is a challenging task that can be met by simultaneous utilization of imaging techniques. Here we focus on the synergy of X-Ray micro-Computed Tomography (μCT), Laser-Induced Breakdown Spectroscopy (LIBS) and Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS) for investigation of various nanoparticles (Gd, Ti, Pb, etc.) distributed in organs. Special emphasis is given to the analysis of nanoparticles in a murine kidney in 3D. Firstly, we have demonstrated the 3D visualization capabilities in soft tissues by iodine staining with μCT. Next, subsequent LIBS and LA-ICP-MS analysis enabled to identify nanoparticles distribution in the sample. Thus, this combination provides a novel analytical approach how to quickly visualize and recognize different elements in soft tissues.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
JA - Electronics and optoelectronics
OECD FORD branch
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Result continuities
Project
<a href="/en/project/LQ1601" target="_blank" >LQ1601: CEITEC 2020</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
13th International Interdisciplinary Meeting on Bioanalysis
ISBN
978-80-904959-4-4
ISSN
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e-ISSN
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Number of pages
3
Pages from-to
253-255
Publisher name
Neuveden
Place of publication
Neuveden
Event location
Brno
Event date
Oct 17, 2016
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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