Calcium Phosphate Foams: Potential Scaffolds for Bone Tissue Modeling in Three Dimensions
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F17%3APU124382" target="_blank" >RIV/00216305:26620/17:PU124382 - isvavai.cz</a>
Result on the web
<a href="https://link.springer.com/protocol/10.1007%2F978-1-4939-7021-6_6" target="_blank" >https://link.springer.com/protocol/10.1007%2F978-1-4939-7021-6_6</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-1-4939-7021-6_6" target="_blank" >10.1007/978-1-4939-7021-6_6</a>
Alternative languages
Result language
angličtina
Original language name
Calcium Phosphate Foams: Potential Scaffolds for Bone Tissue Modeling in Three Dimensions
Original language description
The present method describes the procedure to fabricate calcium phosphate foams with suitable open porosity, pore size, and composition to perform three-dimensional (3D) cell cultures with the objective to simulate the bone tissue microenvironment in vitro. Foams with two compositions but equivalent porosity can be fabricated. On the one hand, hydroxyapatite foams obtained by hydrolysis at 37 °C, with microstructure that mimics the small crystal size of the mineral component of bones, and on the other hand, beta tricalcium phosphate foams with polygonal grains obtained by sintering at 1100 °C. In the first part of the chapter the calcium phosphate foams are briefly described. Afterwards, the foaming process is described in detail, including alternatives to overcome processing problems than can arise. Finally, insights are provided on how to perform 3D cell cultures using the calcium phosphate foams as substrates.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
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OECD FORD branch
30404 - Biomaterials (as related to medical implants, devices, sensors)
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Methods in Molecular Biology
ISBN
978-1-4939-7019-3
Number of pages of the result
16
Pages from-to
79-94
Number of pages of the book
452
Publisher name
Springer
Place of publication
Neuveden
UT code for WoS chapter
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