Microstructure, chemical and biological performance of boron-modified TiCaPCON films
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F19%3APU130330" target="_blank" >RIV/00216305:26620/19:PU130330 - isvavai.cz</a>
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S016943321832573X" target="_blank" >https://www.sciencedirect.com/science/article/pii/S016943321832573X</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.apsusc.2018.09.157" target="_blank" >10.1016/j.apsusc.2018.09.157</a>
Alternative languages
Result language
angličtina
Original language name
Microstructure, chemical and biological performance of boron-modified TiCaPCON films
Original language description
The fabrication of biologically safe materials with enhanced antibacterial characteristics is of great significance. Here we propose B-based therapeutic strategy which offers a good alternative to the widely used approach based on the introduction of most famous bactericidal elements, such as Ag, Cu, and Zn. B-doped TiCaPCON films with 8, 11, and 15 at.% of B were obtained by simultaneous magnetron sputtering of two composite targets (TiC-CaOTi3POx and TiB2) in a gaseous mixture of Ar+15%N2. The B content in the films was controlled by changing magnetron current of the TiB2 target. The B-doped films were thoroughly studied by means of scanning and transmission electron microscopy, high-resolution TEM, X-ray diffraction, Raman spectroscopy, Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy, and glow discharge optical emission spectroscopy. The films were also characterized with respect to surface wettability, boron ion release, and electrochemical characteristics. To test biocompatibility and bioactivity of the films in vitro, spreading, actin cytoskeleton organization, proliferation and osteogenic differentiation of MC3T3-E1 osteoblastic cells grown on the film surface were studied. The antibacterial characteristics of the B-doped TiCaPCON samples against antibiotic- resistant Escherichia coli (E. coli) 261 strains were compared with two-layer BOx/TiCaPCON–B and TiOx/ TiCaPCON–B films obtained by three different methods: (i) deposition of a B2O3 top layer, (ii) annealing and (iii) electrochemical oxidation of the as-deposited B-doped films. The obtained results clearly indicated that all types of B-containing films are not toxic for cells regardless of their surface composition. Antibacterial activity tests revealed that only the sample with B2O3 top layer completely inactivated E. coli cells and prevented biofilm formation. Thus the surface of two-layer B2O3/TiCaPCON–11%B film was simultaneously bactericidal towards E. coli strains and not-t
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10302 - Condensed matter physics (including formerly solid state physics, supercond.)
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Applied Surface Science
ISSN
0169-4332
e-ISSN
1873-5584
Volume of the periodical
465
Issue of the periodical within the volume
1
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
12
Pages from-to
486-497
UT code for WoS article
000449683100056
EID of the result in the Scopus database
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