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Bioactive TiCaPCON-coated PCL nanofibers as a promising material for bone tissue engineering

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F19%3APU134663" target="_blank" >RIV/00216305:26620/19:PU134663 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216224:14740/19:00113735

  • Result on the web

    <a href="https://www.sciencedirect.com/science/article/pii/S0169433219305057?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0169433219305057?via%3Dihub</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.apsusc.2019.02.163" target="_blank" >10.1016/j.apsusc.2019.02.163</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Bioactive TiCaPCON-coated PCL nanofibers as a promising material for bone tissue engineering

  • Original language description

    This work deals with the deposition of bioactive TiCaPCON films onto biodegradable polycaprolactone (PCL) nanofibers using magnetron sputtering for bone tissue engineering. Low melting point of PCL nanofibers requires a careful tuning of processing parameters in order to achieve high film quality and avoid substrate degradation. SEM and XPS analyses showed that, with the magnetron current of 2 A, the TiCaPCON films deposited onto PCL nanofibers and Si wafers exhibit similar chemical states hereby indicating that the nanofiber structure is not affected by the deposition process. In vitro biological tests indicated that the osteoblasts adhesion and proliferation as well the ALP activity can be significantly improved by depositing the TiCaPCON film onto PCL. The reported findings suggest a new strategy for the preparation of biodegradable polymer-based biomaterials for bone tissue engineering.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10403 - Physical chemistry

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2019

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Applied Surface Science

  • ISSN

    0169-4332

  • e-ISSN

    1873-5584

  • Volume of the periodical

    479

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    7

  • Pages from-to

    796-802

  • UT code for WoS article

    000464931800097

  • EID of the result in the Scopus database