The vision of point-of-care PCR tests for the COVID-19 pandemic and beyond

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F20%3APU137559" target="_blank" >RIV/00216305:26620/20:PU137559 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/20:10416062 RIV/00064165:_____/20:10416062
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0165993620302132?casa_token=Z2ZbtTb1LWcAAAAA:u6pRqpDLw8a4YLRIgJDrxE5ECMwLBKGAYLVU_7xizQgoBIyT8yQWdit6se91jm0vDmQz9Cz97A" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0165993620302132?casa_token=Z2ZbtTb1LWcAAAAA:u6pRqpDLw8a4YLRIgJDrxE5ECMwLBKGAYLVU_7xizQgoBIyT8yQWdit6se91jm0vDmQz9Cz97A</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.trac.2020.115984" target="_blank" >10.1016/j.trac.2020.115984</a>

Result language
angličtina
Original language name
The vision of point-of-care PCR tests for the COVID-19 pandemic and beyond
Original language description
Infectious diseases, such as the most recent case of coronavirus disease 2019, have brought the prospect of point-of-care (POC) diagnostic tests into the spotlight. A rapid, accurate, low-cost, and easy-to-use test in the field could stop epidemics before they develop into full-blown pandemics. Unfortunately, despite all the advances, it still does not exist. Here, we critically review the limited number of prototypes demonstrated to date that is based on a polymerase chain reaction (PCR) and has come close to fulfill this vision. We summarize the requirements for the POC PCR tests and then go on to discuss the PCR product-detection methods, the integration of their functional components, the potential applications, and other practical issues related to the implementation of lab-on-a-chip technologies. We conclude our review with a discussion of the latest findings on nucleic acid-based diagnosis. (C) 2020 Elsevier B.V. All rights reserved.
Czech name
—
Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30303 - Infectious Diseases

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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