Femoral bone defect healing using two novel biocompatible degradable materials

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F20%3APU138053" target="_blank" >RIV/00216305:26620/20:PU138053 - isvavai.cz</a>
Alternative codes found
RIV/62157124:16170/20:43878431 RIV/00064165:_____/20:10412855
Result on the web
<a href="https://actavet.vfu.cz/89/2/0163/" target="_blank" >https://actavet.vfu.cz/89/2/0163/</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2754/avb202089020163" target="_blank" >10.2754/avb202089020163</a>

Result language
angličtina
Original language name
Femoral bone defect healing using two novel biocompatible degradable materials
Original language description
This study was conducted as an in vivo experiment in adult miniature pigs with the aim to test two new biomaterials. An iatrogenic defect was made into the central femoral diaphysis in the experimental animals and subsequently fixated by bridging plate osteosynthesis. Into the defect we implanted a cancellous autograft (control group), a pasty injectable scaffold (EXP A), anda porous 3D cylinder (EXP B). Radiological examination was performed in all animals at 0, 10, 20, 30 weeks after surgical procedure and histological assessment was performed. In the newly formed bone the osteoblastic activity was monitored. In terms of radiology, the most effective method was observed in the control group (completely healed 100%) compared to experimental groups EXP A (70.0%) and EXP B (62.5%).
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
40301 - Veterinary science

Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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