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Nanostructured Zirconium-Oxide Bioceramic Coatings Derived from the Anodized Al/Zr Metal Layers

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F21%3APU141172" target="_blank" >RIV/00216305:26620/21:PU141172 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216224:14110/21:00123977

  • Result on the web

    <a href="https://onlinelibrary.wiley.com/doi/10.1002/admi.202100256?af=R" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1002/admi.202100256?af=R</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1002/admi.202100256" target="_blank" >10.1002/admi.202100256</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Nanostructured Zirconium-Oxide Bioceramic Coatings Derived from the Anodized Al/Zr Metal Layers

  • Original language description

    Here, zirconium-oxide ceramic coatings comprising arrays of 3D nanostructures are electrochemically synthesized, ranging in shape, size, spacing, and population density, termed as the nanomounds (o approximate to 65 nm), nanopillars (o approximate to 130 nm), and nanostumps (o approximate to 220 nm). The nanostructured coatings, alongside a flat ZrO2 anodic film, are explored as a potential biomaterial in experiments with Saos-2 cells. All coatings reveal no cytotoxicity to living cells. The population density and spreading area of the cells, being the largest on the flat film, slightly decrease with increasing nanostructure dimensions. The cells progressively proliferate on all the surfaces, the nanomounds and, especially, nanopillars promoting the best viabilities and proliferation rates. The flat, nanomound, and nanopillar coatings promote the well-defined organizations of actin filaments across the entire cell bodies with no disruption in the cytoskeletal network and the mature large dash-shaped focal adhesions. The highest activity of alkaline phosphatase and the biggest deposition of a mineralization-competent extracellular matrix occur on the nanopillar array, the other nanostructures showing a better result than the flat coating, though. The differences, paradoxes, and regularities in the cell responses are explained through the detailed consideration of the coating morphologies, surface chemistries, and processes at the cell/surface interfaces.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    20506 - Coating and films

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Advanced Materials Interfaces

  • ISSN

    2196-7350

  • e-ISSN

  • Volume of the periodical

    neuveden

  • Issue of the periodical within the volume

    10

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    14

  • Pages from-to

    1-14

  • UT code for WoS article

    000666886600001

  • EID of the result in the Scopus database

    2-s2.0-85108858472