Nanostructured Zirconium-Oxide Bioceramic Coatings Derived from the Anodized Al/Zr Metal Layers
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F21%3APU141172" target="_blank" >RIV/00216305:26620/21:PU141172 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/21:00123977
Result on the web
<a href="https://onlinelibrary.wiley.com/doi/10.1002/admi.202100256?af=R" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1002/admi.202100256?af=R</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/admi.202100256" target="_blank" >10.1002/admi.202100256</a>
Alternative languages
Result language
angličtina
Original language name
Nanostructured Zirconium-Oxide Bioceramic Coatings Derived from the Anodized Al/Zr Metal Layers
Original language description
Here, zirconium-oxide ceramic coatings comprising arrays of 3D nanostructures are electrochemically synthesized, ranging in shape, size, spacing, and population density, termed as the nanomounds (o approximate to 65 nm), nanopillars (o approximate to 130 nm), and nanostumps (o approximate to 220 nm). The nanostructured coatings, alongside a flat ZrO2 anodic film, are explored as a potential biomaterial in experiments with Saos-2 cells. All coatings reveal no cytotoxicity to living cells. The population density and spreading area of the cells, being the largest on the flat film, slightly decrease with increasing nanostructure dimensions. The cells progressively proliferate on all the surfaces, the nanomounds and, especially, nanopillars promoting the best viabilities and proliferation rates. The flat, nanomound, and nanopillar coatings promote the well-defined organizations of actin filaments across the entire cell bodies with no disruption in the cytoskeletal network and the mature large dash-shaped focal adhesions. The highest activity of alkaline phosphatase and the biggest deposition of a mineralization-competent extracellular matrix occur on the nanopillar array, the other nanostructures showing a better result than the flat coating, though. The differences, paradoxes, and regularities in the cell responses are explained through the detailed consideration of the coating morphologies, surface chemistries, and processes at the cell/surface interfaces.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
20506 - Coating and films
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Advanced Materials Interfaces
ISSN
2196-7350
e-ISSN
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Volume of the periodical
neuveden
Issue of the periodical within the volume
10
Country of publishing house
DE - GERMANY
Number of pages
14
Pages from-to
1-14
UT code for WoS article
000666886600001
EID of the result in the Scopus database
2-s2.0-85108858472