Lumbar Interbody Fusion Conducted on a Porcine Model with a Bioresorbable Ceramic/Biopolymer Hybrid Implant Enriched with Hyperstable Fibroblast Growth Factor 2
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F21%3APU141827" target="_blank" >RIV/00216305:26620/21:PU141827 - isvavai.cz</a>
Alternative codes found
RIV/00027162:_____/21:N0000097 RIV/68378041:_____/21:00553162 RIV/67985891:_____/21:00553162 RIV/00216224:14110/21:00122158 and 3 more
Result on the web
<a href="https://www.mdpi.com/2227-9059/9/7/733" target="_blank" >https://www.mdpi.com/2227-9059/9/7/733</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/biomedicines9070733" target="_blank" >10.3390/biomedicines9070733</a>
Alternative languages
Result language
angličtina
Original language name
Lumbar Interbody Fusion Conducted on a Porcine Model with a Bioresorbable Ceramic/Biopolymer Hybrid Implant Enriched with Hyperstable Fibroblast Growth Factor 2
Original language description
An experimental animal study was designed to investigate the intervertebral fusion efficiency and safety of a bioresorbable ceramic/biopolymer hybrid implant enriched with FGF2-STAB(R) in comparison with a tricortical bone autograft used as a gold standard. Twenty-four experimental pigs underwent L2/3 discectomy with implantation of either the tricortical iliac crest bone autograft or the bioresorbable hybrid implant (BHI) followed by lateral intervertebral fixation. The quality of spinal fusion was assessed by micro-computed tomography (micro-CT), biomechanical testing, and histological examination at both 8 and 16 weeks after the surgery.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30404 - Biomaterials (as related to medical implants, devices, sensors)
Result continuities
Project
<a href="/en/project/NV17-31276A" target="_blank" >NV17-31276A: Comprehensive pre-clinical evaluation of lateral lumbar spine fusion with hybrid biodegradable nanocomposite porous implant.</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Biomedicines
ISSN
2227-9059
e-ISSN
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Volume of the periodical
9
Issue of the periodical within the volume
7
Country of publishing house
CH - SWITZERLAND
Number of pages
25
Pages from-to
733-758
UT code for WoS article
000676188200001
EID of the result in the Scopus database
2-s2.0-85112635586