Self-Propelled Magnetic Dendrite-Shaped Microrobots for Photodynamic Prostate Cancer Therapy
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F22%3APU147075" target="_blank" >RIV/00216305:26620/22:PU147075 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/22:10449885 RIV/62156489:43210/22:43922257 RIV/00216224:14110/22:00127215 RIV/61989100:27240/22:10251360
Result on the web
<a href="https://onlinelibrary.wiley.com/doi/10.1002/anie.202213505" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1002/anie.202213505</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/anie.202213505" target="_blank" >10.1002/anie.202213505</a>
Alternative languages
Result language
angličtina
Original language name
Self-Propelled Magnetic Dendrite-Shaped Microrobots for Photodynamic Prostate Cancer Therapy
Original language description
Photocatalytic micromotors that exhibit wireless and controllable motion by light have been extensively explored for cancer treatment by photodynamic therapy (PDT). However, overexpressed glutathione (GSH) in the tumor microenvironment can down-regulate the reactive oxygen species (ROS) level for cancer therapy. Herein, we present dendrite-shaped light-powered hematite microrobots as an effective GSH depletion agent for PDT of prostate cancer cells. These hematite microrobots can display negative phototactic motion under light irradiation and flexible actuation in a defined path controlled by an external magnetic field. Non-contact transportation of micro-sized cells can be achieved by manipulating the microrobot's motion. In addition, the biocompatible microrobots induce GSH depletion and greatly enhance PDT performance. The proposed dendrite-shaped hematite microrobots contribute to developing dual light/magnetic field-powered micromachines for the biomedical field.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10405 - Electrochemistry (dry cells, batteries, fuel cells, corrosion metals, electrolysis)
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
ISSN
1433-7851
e-ISSN
1521-3773
Volume of the periodical
61
Issue of the periodical within the volume
48
Country of publishing house
DE - GERMANY
Number of pages
8
Pages from-to
„“-„“
UT code for WoS article
000871719800001
EID of the result in the Scopus database
2-s2.0-85140372389