OLEYL-HYALURONAN SELF-ASSEMBLY AND ITS INTERACTIONS WITH BOVINE SERUM ALBUMIN
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F22%3APU151710" target="_blank" >RIV/00216305:26620/22:PU151710 - isvavai.cz</a>
Result on the web
<a href="https://www.webofscience.com/wos/woscc/full-record/WOS:001249624200024" target="_blank" >https://www.webofscience.com/wos/woscc/full-record/WOS:001249624200024</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
OLEYL-HYALURONAN SELF-ASSEMBLY AND ITS INTERACTIONS WITH BOVINE SERUM ALBUMIN
Original language description
Oleyl-hyaluronan (O-HA) is an amphiphilic polysaccharide that can be used as a drug carrier. Its self-assembly was improved when using a solvent with ions due to charge compensation on the HA backbone. Moreover, the functional properties such as drug loading capacity and its penetration into the skin were enhanced. Interactions with serum proteins are often considered a bottleneck for carriers' application. Interactions of O-HA and bovine serum albumin (BSA) were elucidated by various techniques and divided into three regimes. Structural changes were found and described. Resulting system retained the drug effectively.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
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OECD FORD branch
10404 - Polymer science
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
PROCEEDINGS OF THE 18TH INTERNATIONAL CONFERENCE ON POLYSACCHARIDES-GLYCOSCIENCE
ISBN
978-80-88307-12-9
ISSN
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e-ISSN
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Number of pages
4
Pages from-to
110-113
Publisher name
Neuveden
Place of publication
neuveden
Event location
Praha
Event date
Nov 9, 2022
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
001249624200024