An investigation on the multiple roles of CeO2 nanoparticle in electrochemical sensing: Biomimetic activity and electron acceptor

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F23%3APU148293" target="_blank" >RIV/00216305:26620/23:PU148293 - isvavai.cz</a>

Alternative codes found

RIV/62156489:43210/23:43923176

Result on the web

<a href="https://www-sciencedirect-com.ezproxy.lib.vutbr.cz/science/article/pii/S1572665723001613" target="_blank" >https://www-sciencedirect-com.ezproxy.lib.vutbr.cz/science/article/pii/S1572665723001613</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jelechem.2023.117301" target="_blank" >10.1016/j.jelechem.2023.117301</a>

Result language

angličtina

Original language name

An investigation on the multiple roles of CeO2 nanoparticle in electrochemical sensing: Biomimetic activity and electron acceptor

Original language description

Nanomaterials with enzyme-like activity (nanozymes) are known to be suitable alternatives for natural enzymes tolerating unfavorable pH and temperature conditions. The enzyme-like activity of CeO2 nanoparti-cles was already reported and used in electrochemical sensing, where the peroxidase or oxidase-like activities of CeO2 NPs are mainly used. This work aims to justify the role/s that CeO2 may play in electrochemical sens -ing as a nanozyme and acts as a mediator. To this end, a reduced graphene oxide-CeO2 was prepared and used in two electrochemical sensing configurations. In first configuration, H2O2 reduction was catalyzed at the glassy carbon electrode modified with the rGO-CeO2 nanocomposite (rGO-CeO2 NC). The reduction current obtained upon the presence of H2O2 was attributed to a mediator role having a linear range of 100.0-800.0 mu mol L-1 with a limit of detection (LOD) and limit of quantification (LOQ) of 15.9 mu mol L-1 and 52.9 mu mol L-1, respectively. In another configuration, glucose oxidase was used as a model enzyme with the rGO-CeO2 NC. The oxidation signal obtained upon adding glucose was attributed to the electron-accepting role of the CeO2 NPs. The analytical figures of merit obtained for both configurations indicated their high sen-sitivity, selectivity, and reproducibility. The linear detection range for the nanozyme-enzyme cascade system was 100.0-800.0 mu mol L-1 with a LOD and LOQ of 18.7 mu mol L-1 and 62.3 mu mol L-1, respectively. Moreover, the flow injection analysis was enabled due to the short response time in analysis with the prepared sensor. The possibility for applying the developed nanozyme in nanozyme-enzyme cascade system in clinical and food analysis for determination of glucose was verified by studying the interference of various compounds similar to glucose in structure and typical drugs taken by diabetic patients.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10405 - Electrochemistry (dry cells, batteries, fuel cells, corrosion metals, electrolysis)

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

JOURNAL OF ELECTROANALYTICAL CHEMISTRY

ISSN

1572-6657

e-ISSN

1873-2569

Volume of the periodical

935

Issue of the periodical within the volume

117301

Country of publishing house

CH - SWITZERLAND

Number of pages

11

Pages from-to

1-11

UT code for WoS article

000956549100001

EID of the result in the Scopus database

2-s2.0-85150076394