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Ex-vivo Evaluation of Newly Formed Bone After Lumbar Interbody Fusion Surgery Using X-ray Micro Computed Tomography

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F23%3APU150120" target="_blank" >RIV/00216305:26620/23:PU150120 - isvavai.cz</a>

  • Result on the web

    <a href="https://link.springer.com/chapter/10.1007/978-981-16-6775-6_9" target="_blank" >https://link.springer.com/chapter/10.1007/978-981-16-6775-6_9</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1007/978-981-16-6775-6_9" target="_blank" >10.1007/978-981-16-6775-6_9</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Ex-vivo Evaluation of Newly Formed Bone After Lumbar Interbody Fusion Surgery Using X-ray Micro Computed Tomography

  • Original language description

    Many novel biomaterials are recently investigated for use in spinal fusion surgery, especially in lumbar interbody fusion. The X-ray microCT as a tool is widely used for evaluating how successfully those biomaterials can perform a vertebral fusion. However, the current methodologies of microCT image assessment are based on visual evaluation by the operator. In this paper, we propose a methodology for how such biomaterials can be investigated in pre-clinical studies by investigating fused vertebrae morphology. We utilized microCT scans of pigs’ fused vertebrae to develop a fully automatic approach, which can characterize the morphometry of the bone in the fused region. A surface mesh model was created to extract the newly formed bone tissue between fused vertebrae in the microCT data. Extracted bone tissue was consequently evaluated according to the selected morphometric parameters. Characterization of the newly formed bone properties in the intervertebral area can be utilized to evaluate the osteogenesis function of implants used in lumbar interbody fusion surgery.

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

  • OECD FORD branch

    20601 - Medical engineering

Result continuities

  • Project

    <a href="/en/project/EF19_073%2F0016948" target="_blank" >EF19_073/0016948: Quality internal grants at BUT</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2023

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    Medical Imaging and Computer-Aided Diagnosis

  • ISBN

    978-981-16-6774-9

  • ISSN

    1876-1100

  • e-ISSN

  • Number of pages

    10

  • Pages from-to

    101-110

  • Publisher name

    Springer Nature Singapore

  • Place of publication

    Singapore

  • Event location

    University of Leicester, UK

  • Event date

    Nov 20, 2022

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article