Defining the seriousness of proliferative vitreoretinopathy by aspiration of cytokines from the anterior chamber

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00669806%3A_____%2F13%3A10139746" target="_blank" >RIV/00669806:_____/13:10139746 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.2217/bmm.13.65" target="_blank" >http://dx.doi.org/10.2217/bmm.13.65</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2217/bmm.13.65" target="_blank" >10.2217/bmm.13.65</a>

Result language
angličtina
Original language name
Defining the seriousness of proliferative vitreoretinopathy by aspiration of cytokines from the anterior chamber
Original language description
Proliferative vitreoretinopathy is the major cause of retinal detachment surgery failure. Our prospective cohort study of 27 eyes aimed to determine intraocular levels of growth factors and cytokines in patients with retinal detachment with various degrees of severity of proliferative vitreoretinopathy using multiplex xMAP((R)) Technology. Patients & methods: The concentrations of 12 proangiogenic, antiangiogenic, inflammatory and neurotrophic factors were measured from 0.05-ml samples of intraocular fluid using multiplex xMAP Technology. The results were compared with levels of various factors, which were measured in samples from the control group of 31 eyes prior to senile cataract surgery. Results: The concentration of the MCP-1 cytokine was found to be higher in eyes with retinal detachment compared with the control group. The concentration of VEGF was found to be higher in eyes with retinal detachment complicated with proliferative vitreoretinopathy compared with the uncomplicated
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FF - ENT (ie. ear, nose, throat), ophthalmology, dentistry
OECD FORD branch
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Project
<a href="/en/project/NS10251" target="_blank" >NS10251: Assessment of angiogenesis promotors in intraocular fluid by multiplex analysis</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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