Right Ventricular Pressure Overload and Pathophysiology of Growing Porcine Biomodel

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00669806%3A_____%2F16%3A10326774" target="_blank" >RIV/00669806:_____/16:10326774 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11140/16:10326774
Result on the web
<a href="http://dx.doi.org/10.1007/s00246-016-1463-y" target="_blank" >http://dx.doi.org/10.1007/s00246-016-1463-y</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00246-016-1463-y" target="_blank" >10.1007/s00246-016-1463-y</a>

Result language
angličtina
Original language name
Right Ventricular Pressure Overload and Pathophysiology of Growing Porcine Biomodel
Original language description
We developed and validated experimental model of increased right ventricular afterload by pulmonary artery banding in a large growing animal. Our study did not show evidence of haemodynamic benefit of oral enoximone treatment in this setting. We have shown that pulmonary artery banding leads to morphological myocardial changes including apoptosis, proliferation and fibrosis affecting myocardium of the right and left heart. No protective effect of oral administration of enoximone was demonstrated either.
Czech name
—
Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FG - Paediatrics
OECD FORD branch
—

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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