Relationship between hsTnI and coronary stenosis in asymptomatic women with rheumatoid arthritis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00669806%3A_____%2F16%3A10328100" target="_blank" >RIV/00669806:_____/16:10328100 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11140/16:10328100
Result on the web
<a href="http://bmccardiovascdisord.biomedcentral.com/articles/10.1186/s12872-016-0359-3" target="_blank" >http://bmccardiovascdisord.biomedcentral.com/articles/10.1186/s12872-016-0359-3</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1186/s12872-016-0359-3" target="_blank" >10.1186/s12872-016-0359-3</a>
Alternative languages
Result language
angličtina
Original language name
Relationship between hsTnI and coronary stenosis in asymptomatic women with rheumatoid arthritis
Original language description
Rheumatoid arthritis (RA) is a condition associated with accelerated progression of atherosclerosis in affected individuals. Myocardial assessment using exercise testing in such patients, however, is often difficult to perform. Our objective was to determine the factors associated with severe coronary stenosis using computed tomography (CT) angiography of the coronary arteries in asymptomatic patients with RA. Forty-four women with RA were examined using CT angiography to detect atherosclerotic involvement and significant coronary stenosis (>50 %). CT findings were correlated with the cardiovascular risk score, and with classical and most recent parameters of atherosclerosis. CT angiography of the coronary arteries revealed severe stenosis (>70 %) in 9 % of patients. High-sensitivity troponin I level was associated with severe coronary stenosis (odds ratio 6.37; 95 % confidence interval 1.53 MINUS SIGN 26.48; P = 0.011). Adjustment for confounders did not alter this result (P = 0.039). In contrast, classical and modified Systemic Coronary Risk Evaluation scores had no value in predicting severe stenosis (P GREATER-THAN OR EQUAL TO 0.49). The present study showed the possible benefits of a coronary CT angiography in women with RA and asymptomatic ischemic coronary heart disease. Increased levels of high-sensitivity troponin I may be a potential indication for this type of examination. However, further studies are needed to confirm these results.
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FA - Cardiovascular diseases including cardio-surgery
OECD FORD branch
—
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
BMC Cardiovascular Disorders
ISSN
1471-2261
e-ISSN
—
Volume of the periodical
16
Issue of the periodical within the volume
September
Country of publishing house
GB - UNITED KINGDOM
Number of pages
8
Pages from-to
—
UT code for WoS article
000385773800001
EID of the result in the Scopus database
2-s2.0-84989282628