Aggressive TFEB-rearranged renal cell carcinoma mimicking chromophobe and clear cell renal cell carcinoma
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00669806%3A_____%2F19%3A10395311" target="_blank" >RIV/00669806:_____/19:10395311 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11140/19:10395311
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=coGE1n5-kz" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=coGE1n5-kz</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/pin.12744" target="_blank" >10.1111/pin.12744</a>
Alternative languages
Result language
angličtina
Original language name
Aggressive TFEB-rearranged renal cell carcinoma mimicking chromophobe and clear cell renal cell carcinoma
Original language description
MiT family translocation renal cell carcinoma (RCC) includes Xp11 translocation RCC and t(6;11) RCC. The t (6;11)RCC exhibits MALAT1-TFEB gene fusion and is less common than Xp11 translocation RCC. Typical t(6;11) RCC shows solid alveolar growth composed of eosinophilic large cells mixed with clear cells, and rosette-like structures composed of lymphocyte-like small cells around an eosinophilic basement membrane material. Tubular and papillary architecture could also be seen in some parts. However, t (6;11) RCC may possibly have variable morphological patterns, such as Xp11.2 RCC. Some t(6;11) RCCs were reported to resemble clear cell RCC (CRCC),1 chromophobe RCC (ChRCC),1 and Xp11.2 translocation RCC.2 Recently, it was suggested that TFEB-amplified RCC is a unique tumor type.3,4 Some t(6;11) RCCs with TFEB amplification have been reported, and it was suggested that some RCCs develop in older patients with aggressive behavior, compared to t(6;11) RCC without TFEB amplification.2,3 To our knowledge, this is the first report of recurrent TFEB-rearrangement RCC with TFEB amplification mimicking ChRCC and CRCC.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30109 - Pathology
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Pathology International
ISSN
1320-5463
e-ISSN
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Volume of the periodical
69
Issue of the periodical within the volume
1
Country of publishing house
JP - JAPAN
Number of pages
3
Pages from-to
51-53
UT code for WoS article
000457014900008
EID of the result in the Scopus database
2-s2.0-85059663271