The prognosis and therapeutic management of patients hospitalized for heart failure in 2010-2020
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00669806%3A_____%2F22%3A10444078" target="_blank" >RIV/00669806:_____/22:10444078 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11140/22:10444078 RIV/00064190:_____/22:N0000028
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=JFeBK1F4R6" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=JFeBK1F4R6</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5507/bp.2022.020" target="_blank" >10.5507/bp.2022.020</a>
Alternative languages
Result language
angličtina
Original language name
The prognosis and therapeutic management of patients hospitalized for heart failure in 2010-2020
Original language description
Aims. We analyzed the mortality risk and its predictors in patients hospitalized for heart failure (HF). Methods. Patients discharged from hospitalization for acute decompensation of HF in 2010- 2020 and younger than 86 years were followed (n=4097). We assessed the incidence and trends of all-cause death, its main predictors, and the pharmacotherapy recommended at discharge from the hospital. Results. The 30 days all-cause mortality was in discharged patients 3.2%, while 1-year 20.4% and 5-years 55.4%. We observed a modest trend to decreased 1-year mortality risk over time. Any increase of year of hospitalization by one was associated with about 5% lower risk in the fully adjusted model. Regarding predictors of 1-year mortality risk, a positive association was found for age over 65, history of malignancy, and peak brain natriuretic peptide during hospitalization >= 10times higher than normal concentration. In contrast, as protective factors, we identified LDL >= 1.8 mmol/L, treatment with beta-blockers, renin-angiotensin axis blockers, statins, and implanted cardioverter in the same regression model. The ejection fraction category and primary etiology of HF (coronary artery disease vs. others) did not significantly affect the mortality risk in a fully adjusted model. Conclusions. Despite advances in cardiovascular disease management over the last two decades, the prognosis of patients hospitalized for heart failure remained highly unfavorable.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30201 - Cardiac and Cardiovascular systems
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Biomedical Papers
ISSN
1213-8118
e-ISSN
1804-7521
Volume of the periodical
166
Issue of the periodical within the volume
3
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
10
Pages from-to
312-321
UT code for WoS article
000790590300001
EID of the result in the Scopus database
2-s2.0-85138142072