Enhanced vitamin K expenditure as a major contributor to vitamin K deficiency in COVID-19
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00669806%3A_____%2F22%3A10453765" target="_blank" >RIV/00669806:_____/22:10453765 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11140/22:10453765
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=cCZoMQEUhp" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=cCZoMQEUhp</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.ijid.2022.10.030" target="_blank" >10.1016/j.ijid.2022.10.030</a>
Alternative languages
Result language
angličtina
Original language name
Enhanced vitamin K expenditure as a major contributor to vitamin K deficiency in COVID-19
Original language description
OBJECTIVES: Vitamin K deficiency consistently associates with worse clinical outcome in COVID-19 patients. However, whether this is due to increased expenditure during inflammation or poor vitamin K status prior to infection remained unknown. METHODS: Dp-ucMGP levels of 128 individuals were measured for the post-MONICA study and were compared to SARS-CoV-2 PCR testing results. RESULTS: Dp-ucMGP levels prior to COVID-19 infection were not significantly different comparing PCR-negative, PCR-positive and not hospitalized, and PCR-positive and hospitalized patients. CONCLUSION: In this study, we demonstrate normal vitamin K status prior to infection in SARS-CoV-2 positive patients, supporting the theory of increased utilisation during disease.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30201 - Cardiac and Cardiovascular systems
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International Journal of Infectious Diseases
ISSN
1201-9712
e-ISSN
1878-3511
Volume of the periodical
125
Issue of the periodical within the volume
December
Country of publishing house
GB - UNITED KINGDOM
Number of pages
3
Pages from-to
275-277
UT code for WoS article
000965649700030
EID of the result in the Scopus database
2-s2.0-85143119372