Treatment of older patients with multiple sclerosis: Results of an International Delphi Survey
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00669806%3A_____%2F23%3A10471038" target="_blank" >RIV/00669806:_____/23:10471038 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11140/23:10471038
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=W10rO9mgxO" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=W10rO9mgxO</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1177/20552173231198588" target="_blank" >10.1177/20552173231198588</a>
Alternative languages
Result language
angličtina
Original language name
Treatment of older patients with multiple sclerosis: Results of an International Delphi Survey
Original language description
BackgroundPeople over age 50-55 have historically been excluded from randomized clinical trials for multiple sclerosis (MS). However, more than half of those living with an MS diagnosis are over 55.ObjectiveExplore the unique considerations of treating older people with MS (PwMS) using an iterative and structured Delphi-based assessment to gather expert opinions.MethodsEight MS neurologists with an interest in older PwMS developed a 2-round survey. Survey respondents were qualified neurologists with >= 3 years' experience, personally responsible for treatment decisions, and treating >= 20 patients per month, of whom >= 10% were >= 50 years old. Consensus was defined as >= 75% agreement on questions with categorical responses or as a mean score >= 4 on questions with numerical responses.ResultsIn Survey 1, 224 neurologists responded; 180 of these completed Survey 2. Limited consensus was reached with varying levels of agreement on several topics including identification and assessment of older patients; factors relating to treatment decisions including immunosenescence and comorbidities; considerations for high-efficacy treatments; de-escalation or discontinuation of treatment; effects of COVID-19; and unmet needs for treating this population.ConclusionThe results of this Delphi process highlight the need for targeted studies to create guidance for the care of older PwMS.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30103 - Neurosciences (including psychophysiology)
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Multiple Sclerosis Journal - Experimental, Translational and Clinical
ISSN
2055-2173
e-ISSN
2055-2173
Volume of the periodical
9
Issue of the periodical within the volume
3
Country of publishing house
GB - UNITED KINGDOM
Number of pages
11
Pages from-to
20552173231198588
UT code for WoS article
001093076700001
EID of the result in the Scopus database
2-s2.0-85176422596