Incidence and outcome of central nervous system relapse after hematopoietic stem cell transplantation in patients suffering from acute myeloid leukemia and acute lymphoblastic leukemia: a study from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00669806%3A_____%2F24%3A10478537" target="_blank" >RIV/00669806:_____/24:10478537 - isvavai.cz</a>
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=2jwBLwiR66" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=2jwBLwiR66</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3324/haematol.2023.284858" target="_blank" >10.3324/haematol.2023.284858</a>
Alternative languages
Result language
angličtina
Original language name
Incidence and outcome of central nervous system relapse after hematopoietic stem cell transplantation in patients suffering from acute myeloid leukemia and acute lymphoblastic leukemia: a study from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation
Original language description
The retrospective, multricenter EBMT study was performed to evaluate the incidence and outcome of CNS relapse after allogeneic transplantation in patients suffering from AML and ALL. Study included 7,991 patients: 5,724 (71.6%) AML, and 2,267 (28.4%), all patients were transplantedbetween 1996 and 2016. Ninety-one patients of the 7,991 (1.1%) experienced CNS relapse after allo-HSCT. The relapse was more frequent in ALL than in AML. CNS relapse was a rare event, however the prognosis was dismal. Around half the patients could achieve CR, but the OS remained low (8.2% in AML, 15.5% in ALL at 5 years). OS was better in isolated CNS (37.5% vs. 6.7% at 2 years).
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30205 - Hematology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Haematologica
ISSN
0390-6078
e-ISSN
1592-8721
Volume of the periodical
109
Issue of the periodical within the volume
7
Country of publishing house
IT - ITALY
Number of pages
5
Pages from-to
2346-2350
UT code for WoS article
001263361100041
EID of the result in the Scopus database
2-s2.0-85197791112