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Albumin, Septic Shock, and the Kidney: Dissecting the Gordian Knot

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00669806%3A_____%2F25%3A10496692" target="_blank" >RIV/00669806:_____/25:10496692 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11140/25:10496692

  • Result on the web

    <a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=Nr1iU0pg-N" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=Nr1iU0pg-N</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.chest.2024.11.013" target="_blank" >10.1016/j.chest.2024.11.013</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Albumin, Septic Shock, and the Kidney: Dissecting the Gordian Knot

  • Original language description

    Albumin is a water soluble, nonglycosylated protein that is largely responsible for plasma oncotic pressure. It binds cations, fatty acids, bilirubin, and hormones. In addition, albumin acts as carrier for medication and has antioxidant, antiinflammatory and acid base-buffering properties. Patients with sepsis often display hypoalbuminemia of multifactorial cause. Therefore, there is a strong physiologic rationale to use albumin solutions as resuscitation fluids during sepsis. A recent survey on albumin uses in shock, however, documented wildly variable attitudes of intensivists. More than one-third of clinicians would never or rarely use albumin in septic shock, and roughly one-third of them would infuse it frequently or almost always in these patients.

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

  • OECD FORD branch

    30221 - Critical care medicine and Emergency medicine

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2025

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů