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The role of radiotherapy in the treatment of oligometastatic non-small cell lung cancer

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00669806%3A_____%2F25%3A10500653" target="_blank" >RIV/00669806:_____/25:10500653 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11140/25:10500653

  • Result on the web

    <a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=FkV67Dij5R" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=FkV67Dij5R</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.5603/rpor.107745" target="_blank" >10.5603/rpor.107745</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    The role of radiotherapy in the treatment of oligometastatic non-small cell lung cancer

  • Original language description

    In the recent years, the clinical stage where the cancer has spread beyond the primary site, but has not yet metastasised extensively, and which is known as oligometastatic disease (OMD), has become an object of interest to radiation oncologists. OMD is a kind of an &quot;umbrella term&quot; for a variety of clinical situations.This review focuses on the role of radiotherapy (RT) in the treatment of oligometastatic non-small cell lung cancer (OM-NSCLC). Currently, a wide range of techniques and fractionation regimens are used to treat OM-NSCLC and, unfortunately, it is not yet possible to determine which approach is the most effective. Therefore, more than ever, we should use the concept of risk-adapted RT and consider many factors when choosing the fractionation regimen and total dose applied. For different clinical scenarios, we set different treatment goals and derive different RT techniques and fractionations.Oligoprogression (OP) is a specific type of OMD that is increasingly encountered in clinical situations, probably due to the increased use of targeted therapy and the subsequent acquired resistance of a certain subpopulation of tumour cells. OP is the progression of a limited number of metastases after an initial response to systemic therapy. The rationale for using RT in areas of progression is to overcome tumour resistance in these progressive lesions.A number of trials are currently underway to find the optimal RT techniques for the most appropriate patients at a precise clinical stage.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30204 - Oncology

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2025

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Reports of Practical Oncology and Radiotherapy

  • ISSN

    1507-1367

  • e-ISSN

    2083-4640

  • Volume of the periodical

    30

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    PL - POLAND

  • Number of pages

    11

  • Pages from-to

    385-395

  • UT code for WoS article

    001563418900001

  • EID of the result in the Scopus database

    2-s2.0-105022199841