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Oral rivaroxaban for symptomatic venous thromboembolism

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F10%3A00101810" target="_blank" >RIV/00843989:_____/10:00101810 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1056/NEJMoa1007903" target="_blank" >http://dx.doi.org/10.1056/NEJMoa1007903</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1056/NEJMoa1007903" target="_blank" >10.1056/NEJMoa1007903</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Oral rivaroxaban for symptomatic venous thromboembolism

  • Original language description

    Rivaroxaban, an oral factor Xa inhibitor, may provide a simple, fixed-dose regimen for treating acute deep-vein thrombosis (DVT) and for continued treatment, without the need for laboratory monitoring. We conducted an open-label, randomized, event-driven, noninferiority study that compared oral rivaroxaban alone (15 mg twice daily for 3 weeks, followed by 20 mg once daily) with subcutaneous enoxaparin followed by a vitamin K antagonist (either warfarin or acenocoumarol) for 3, 6, or 12 months in patients with acute, symptomatic DVT. In parallel, we carried out a double-blind, randomized, event-driven superiority study that compared rivaroxaban alone (20 mg once daily) with placebo for an additional 6 or 12 months in patients who had completed 6 to 12 months offor an additional 6 or 12 months in patients who had completed 6 to 12 months of

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FA - Cardiovascular diseases including cardio-surgery

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    N - Vyzkumna aktivita podporovana z neverejnych zdroju

Others

  • Publication year

    2010

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    New England Journal of Medicine

  • ISSN

    0028-4793

  • e-ISSN

  • Volume of the periodical

    363

  • Issue of the periodical within the volume

    no.26

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    12

  • Pages from-to

    2499-2510

  • UT code for WoS article

    000285555600005

  • EID of the result in the Scopus database