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<The >role of histone deacetylase inhibitors in patients with relapsed/refractory multiple myeloma

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F14%3AE0103897" target="_blank" >RIV/00843989:_____/14:E0103897 - isvavai.cz</a>

  • Alternative codes found

    RIV/61988987:17110/14:A1501CGS

  • Result on the web

    <a href="http://dx.doi.org/10.3109/10428194.2013.797084" target="_blank" >http://dx.doi.org/10.3109/10428194.2013.797084</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.3109/10428194.2013.797084" target="_blank" >10.3109/10428194.2013.797084</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    <The >role of histone deacetylase inhibitors in patients with relapsed/refractory multiple myeloma

  • Original language description

    Clinical outcomes for patients with multiple myeloma (MM) have improved substantially since the introduction of novel agents including the proteasome inhibitor bortezomib and the immunomodulatory drugs thalidomide and lenalidomide. However, most patientswith MM eventually relapse, and prognosis remains poor among patients with relapsed and/or refractory disease. Combination therapy using agents with different mechanisms of action is emerging as an attractive treatment approach in oncology to increase efficacy and/or overcome resistance to standard treatment regimens. This review discusses unmet needs in the treatment of MM and the development of histone deacetylase inhibitors as a treatment modality for MM.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FD - Oncology and haematology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    N - Vyzkumna aktivita podporovana z neverejnych zdroju

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Leukemia & lymphoma

  • ISSN

    1042-8194

  • e-ISSN

  • Volume of the periodical

    55

  • Issue of the periodical within the volume

    n. 1

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    8

  • Pages from-to

    "p. 11-18"

  • UT code for WoS article

    000329122600006

  • EID of the result in the Scopus database