No-option critical limb ischemia revascularization with stem cell therapy

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F14%3AE0104172" target="_blank" >RIV/00843989:_____/14:E0104172 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
No-option critical limb ischemia revascularization with stem cell therapy
Original language description
AIM AND METHODS: Peripheral arterial occlusive disease (PAOD) has been recognized as a significant factor in the population of patients with critical limb ischemia. In total 49% of patients presenting with a new diabetic foot ulcer had PAOD. Critical limb ischemia (CLI) develops suddenly, and is responsible for 50-67% of all nontraumatic lower extremity amputations. Fifty two per cent of diabetics with CLI die during the 4.5-year follow-up. The SmartPreP2 centrifuge gradient density centrifugation resulted in at least a 7.16 fold concentration of CD34+ cells in the bone marrow concentrate and more than 6.2 fold concentration of mononuclear cells (compared to a sample of BMA aspirate before centrifugation). The gradient density centrifugation increasedthe concentration of platelets about 3.9 fold while preserving the relative concentrations of other cells in the host BMAC. The procedure of stem cells transplantation is performed under intravenous single-shot antibiotics, in order to av
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FP - Other medical fields
OECD FORD branch
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Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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