Diagnosis of extraesophageal reflux in children with chronic otitis media with effusion using Peptest

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F15%3A0104669A" target="_blank" >RIV/00843989:_____/15:0104669A - isvavai.cz</a>

Alternative codes found

RIV/00843989:_____/15:E0104669

Result on the web

<a href="http://dx.doi.org/10.1016/j.ijporl.2015.02.013" target="_blank" >http://dx.doi.org/10.1016/j.ijporl.2015.02.013</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ijporl.2015.02.013" target="_blank" >10.1016/j.ijporl.2015.02.013</a>

Result language

angličtina

Original language name

Diagnosis of extraesophageal reflux in children with chronic otitis media with effusion using Peptest

Original language description

INTRODUCTION: The aim of the study was to investigate whether Peptest, an immunoassay used to detect pepsin, could be used to diagnose extraesophageal reflux (EER) in children with chronic otitis media with effusion (OME). The results obtained using this fast, simple and non-expensive method were compared with the results of previous studies. METHODS: Children 1-7 years old who had been diagnosed with OME and who were undergoing myringotomy with insertion of a ventilation tube were included in the prospective study. Middle ear fluid obtained during myringotomy was analyzed with Peptest to determine the presence of pepsin, and hence EER. RESULTS: Bilateral and unilateral myringotomy was performed in 15/44 (34.1%) and 29/44 (65.9%) children, respectively. Pepsin in the middle ear was detected in 14/44 (31.8%) children and in 19/59 (32.2%) middle ear specimens. Serous and mucous samples were positive for pepsin in 11/32 (34.4%) and 6/27 (22.2%) cases, respectively. Pepsin in the middle ear was detected in 3/7 children (42.9%) with bronchial asthma (p=0.662). CONCLUSIONS: Pepsin was detected in 1/3 of middle ear specimens of patients with OME. These patients probably suffer from more severe reflux and therefore would be potential candidates for antireflux therapy. However, this has to be confirmed in further studies.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FF - ENT (ie. ear, nose, throat), ophthalmology, dentistry

OECD FORD branch

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Project

<a href="/en/project/NT13500" target="_blank" >NT13500: The Diagnostics of Extraesophageal Reflux with the Restech System in Patients with Chronic Rhinosinusitis</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

International journal of pediatric otorhinolaryngology

ISSN

0165-5876

e-ISSN

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Volume of the periodical

79

Issue of the periodical within the volume

n. 5

Country of publishing house

IE - IRELAND

Number of pages

3

Pages from-to

"p. 677-679"

UT code for WoS article

000353604600009

EID of the result in the Scopus database

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