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Cerebellar dysfunction and ataxia in patients with epilepsy: coincidence, consequence, or cause?

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F16%3AE0106002" target="_blank" >RIV/00843989:_____/16:E0106002 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216224:14110/16:00092463

  • Result on the web

    <a href="http://dx.doi.org/10.7916/D8KH0NBT" target="_blank" >http://dx.doi.org/10.7916/D8KH0NBT</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.7916/D8KH0NBT" target="_blank" >10.7916/D8KH0NBT</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Cerebellar dysfunction and ataxia in patients with epilepsy: coincidence, consequence, or cause?

  • Original language description

    Basic epilepsy teachings assert that seizures arise from the cerebral cortex, glossing over infratentorial structures such as the cerebellum that are believed to modulate rather than generate seizures. Nonetheless, ataxia and other clinical findings in epileptic patients are slowly but inevitably drawing attention to this neural node. Tracing the evolution of this line of inquiry from the observed coincidence of cerebellar atrophy and cerebellar dysfunction (most apparently manifested as ataxia) in epilepsy to their close association, this review considers converging clinical, physiological, histological, and neuroimaging evidence that support incorporating the cerebellum into epilepsy pathology. We examine reports of still controversial cerebellar epilepsy, studies of cerebellar stimulation alleviating paroxysmal epileptic activity, studies and case reports of cerebellar lesions directly associated with seizures, and conditions in which ataxia is accompanied by epileptic seizures. Finally, the review substantiates the role of this complex brain structure in epilepsy whether by coincidence, as a consequence of deleterious cortical epileptic activity or antiepileptic drugs, or the very cause of the disease.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FH - Neurology, neuro-surgery, nuero-sciences

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2016

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Tremor and other hyperkinetic movements

  • ISSN

    2160-8288

  • e-ISSN

  • Volume of the periodical

    6

  • Issue of the periodical within the volume

    n. June

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    12

  • Pages from-to

    "p. 1-12"

  • UT code for WoS article

  • EID of the result in the Scopus database