Biobanking - the first step to successful liquid biopsy experiments
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F17%3AE0106558" target="_blank" >RIV/00843989:_____/17:E0106558 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/17:00097853 RIV/65269705:_____/17:00067233
Result on the web
<a href="http://dx.doi.org/10.14735/amko20172S9" target="_blank" >http://dx.doi.org/10.14735/amko20172S9</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.14735/amko20172S9" target="_blank" >10.14735/amko20172S9</a>
Alternative languages
Result language
angličtina
Original language name
Biobanking - the first step to successful liquid biopsy experiments
Original language description
Background: Archiving of biological materials in biobanks is considered to be the initial crucial part of research activities. Most often, biobanks are founded for research purposes since they allow collection of sufficient material for analysis of new or testing of previously identified biomarkers. Biobanking needs to quickly react to current needs of researchers as well as clinicians, it is not a rigid system. Laboratory analyses of monoclonal gammopathies are based on separation of plasma cells from bone marrow of patients. A specific problem is usually a lack of tumor cell fraction, which is due to location of tumor cell in bone marrow in combination with low infiltration. One of the challenges in clinical research is the necessity of changes in biobanking for samples allowing detection of minimal residual disease in the bone marrow but also from peripheral blood by the so-called liquid biopsies. Aim: The aim of this review is to show the importance of archiving biological material in the Czech Republic and to show concrete examples of its usage in hematooncology. Conclusion: A general problem in solving many research questions is the availability of a critical amount of specimens for statistical analysis. Obtaining critical amount of specimens of biological material can be quickly archived by cooperation of biobanks sharing both methodological standards and informations about the availability of samples for research projects.
Czech name
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Czech description
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Classification
Type
J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database
CEP classification
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OECD FORD branch
30204 - Oncology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Klinická onkologie
ISSN
0862-495X
e-ISSN
1802-5307
Volume of the periodical
30
Issue of the periodical within the volume
suppl.2
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
1
Pages from-to
2s9-2s12
UT code for WoS article
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EID of the result in the Scopus database
2-s2.0-85029468163