Outcomes of patients presenting with mild acute respiratory distress syndrome

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F19%3AE0107743" target="_blank" >RIV/00843989:_____/19:E0107743 - isvavai.cz</a>

Result on the web

<a href="https://anesthesiology.pubs.asahq.org/article.aspx?articleid=2717118" target="_blank" >https://anesthesiology.pubs.asahq.org/article.aspx?articleid=2717118</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1097/ALN.0000000000002508" target="_blank" >10.1097/ALN.0000000000002508</a>

Result language

angličtina

Original language name

Outcomes of patients presenting with mild acute respiratory distress syndrome

Original language description

Background: Patients with initial mild acute respiratory distress syndrome are often underrecognized and mistakenly considered to have low disease severity and favorable outcomes. They represent a relatively poorly characterized population that was only classified as having acute respiratory distress syndrome in the most recent definition. Our primary objective was to describe the natural course and the factors associated with worsening and mortality in this population. Methods: This study analyzed patients from the international prospective Large Observational Study to Understand the Global Impact of Severe Acute Respiratory Failure (LUNG SAFE) who had initial mild acute respiratory distress syndrome in the first day of inclusion. This study defined three groups based on the evolution of severity in the first week: “worsening” if moderate or severe acute respiratory distress syndrome criteria were met, “persisting” if mild acute respiratory distress syndrome criteria were the most severe category, and “improving” if patients did not fulfill acute respiratory distress syndrome criteria any more from day 2. Results: Among 580 patients with initial mild acute respiratory distress syndrome, 18% (103 of 580) continuously improved, 36% (210 of 580) had persisting mild acute respiratory distress syndrome, and 46% (267 of 580) worsened in the first week after acute respiratory distress syndrome onset. Global in-hospital mortality was 30% (172 of 576; specifically 10% [10 of 101], 30% [63 of 210], and 37% [99 of 265] for patients with improving, persisting, and worsening acute respiratory distress syndrome, respectively), and the median (interquartile range) duration of mechanical ventilation was 7 (4, 14) days (specifically 3 [2, 5], 7 [4, 14], and 11 [6, 18] days for patients with improving, persisting, and worsening acute respiratory distress syndrome, respectively). Admissions for trauma or pneumonia, higher nonpulmonary sequential organ failure assessment score, low...

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30221 - Critical care medicine and Emergency medicine

Project

—

Continuities

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Anesthesiology

ISSN

0003-3022

e-ISSN

1528-1175

Volume of the periodical

130

Issue of the periodical within the volume

2

Country of publishing house

US - UNITED STATES

Number of pages

21

Pages from-to

263-283

UT code for WoS article

000466747200013

EID of the result in the Scopus database

2-s2.0-85060572037