Elective cancer surgery in COVID-19-Free surgical pathways during the SARS-CoV-2 pandemic: An international, multicenter, comparative cohort study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F21%3AE0108993" target="_blank" >RIV/00843989:_____/21:E0108993 - isvavai.cz</a>

Result on the web

<a href="https://ascopubs.org/doi/pdf/10.1200/JCO.20.01933" target="_blank" >https://ascopubs.org/doi/pdf/10.1200/JCO.20.01933</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1200/JCO.20.01933" target="_blank" >10.1200/JCO.20.01933</a>

Result language

angličtina

Original language name

Elective cancer surgery in COVID-19-Free surgical pathways during the SARS-CoV-2 pandemic: An international, multicenter, comparative cohort study

Original language description

Purpose: As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19-free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. Patients and methods: This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19-free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). Results: Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19-free surgical pathways. Patients who underwent surgery within COVID-19-free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19-free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score-matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19-free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). Conclusion: Within available resources, dedicated COVID-19-free surgical pathways should be es...

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30204 - Oncology

Project

—

Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of clinical oncology

ISSN

0732-183X

e-ISSN

1527-7755

Volume of the periodical

39

Issue of the periodical within the volume

1

Country of publishing house

US - UNITED STATES

Number of pages

13

Pages from-to

66-78

UT code for WoS article

000611172100010

EID of the result in the Scopus database

2-s2.0-85098324528