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Therapeutic drug monitoring guided fluconazole therapy in a patient with cholangitis sepsis

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F22%3AE0109347" target="_blank" >RIV/00843989:_____/22:E0109347 - isvavai.cz</a>

  • Alternative codes found

    RIV/61988987:17110/22:A2302JC3

  • Result on the web

    <a href="https://www.futuremedicine.com/doi/epub/10.2217/pme-2021-0010" target="_blank" >https://www.futuremedicine.com/doi/epub/10.2217/pme-2021-0010</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.2217/pme-2021-0010" target="_blank" >10.2217/pme-2021-0010</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Therapeutic drug monitoring guided fluconazole therapy in a patient with cholangitis sepsis

  • Original language description

    Candida and other fungal species play an increasing role in nosocomial infections, including cholangitis and cholangiosepsis. Early diagnosis and prompt treatment are essential in successful patient outcomes. Fluconazole is an antifungal of choice in fluconazole-sensitive Candida infections. Little information is known about the fluconazole biliary excretion. Decreased tissue penetration may be one of the possible causes of treatment failure. Due to favorable pharmacokinetics, therapeutic drug monitoring of this antifungal has not been recommended routinely. In the presented case we report the successful therapeutic drug monitoring-guided fluconazole treatment in a patient with cholangitis and cholangiosepsis caused by fluconazole-sensitive Candida spp.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30104 - Pharmacology and pharmacy

Result continuities

  • Project

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2022

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Personalized medicine

  • ISSN

    1741-0541

  • e-ISSN

    1744-828X

  • Volume of the periodical

    19

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    6

  • Pages from-to

    9-14

  • UT code for WoS article

    000715367700001

  • EID of the result in the Scopus database

    2-s2.0-85122128628