Patient self-inflicted lung injury - a narrative review of pathophysiology, early recognition, and management options

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F23%3AE0110268" target="_blank" >RIV/00843989:_____/23:E0110268 - isvavai.cz</a>

Alternative codes found

RIV/61988987:17110/23:A2402NNR

Result on the web

<a href="https://www.mdpi.com/2075-4426/13/4/593" target="_blank" >https://www.mdpi.com/2075-4426/13/4/593</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/jpm13040593" target="_blank" >10.3390/jpm13040593</a>

Result language

angličtina

Original language name

Patient self-inflicted lung injury - a narrative review of pathophysiology, early recognition, and management options

Original language description

Patient self-inflicted lung injury (P-SILI) is a life-threatening condition arising from excessive respiratory effort and work of breathing in patients with lung injury. The pathophysiology of P-SILI involves factors related to the underlying lung pathology and vigorous respiratory effort. P-SILI might develop both during spontaneous breathing and mechanical ventilation with preserved spontaneous respiratory activity. In spontaneously breathing patients, clinical signs of increased work of breathing and scales developed for early detection of potentially harmful effort might help clinicians prevent unnecessary intubation, while, on the contrary, identifying patients who would benefit from early intubation. In mechanically ventilated patients, several simple non-invasive methods for assessing the inspiratory effort exerted by the respiratory muscles were correlated with respiratory muscle pressure. In patients with signs of injurious respiratory effort, therapy aimed to minimize this problem has been demonstrated to prevent aggravation of lung injury and, therefore, improve the outcome of such patients. In this narrative review, we accumulated the current information on pathophysiology and early detection of vigorous respiratory effort. In addition, we proposed a simple algorithm for prevention and treatment of P-SILI that is easily applicable in clinical practice.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30221 - Critical care medicine and Emergency medicine

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of personalized medicine

ISSN

2075-4426

e-ISSN

2075-4426

Volume of the periodical

13

Issue of the periodical within the volume

article 593

Country of publishing house

CH - SWITZERLAND

Number of pages

14

Pages from-to

1-14

UT code for WoS article

000977771100001

EID of the result in the Scopus database

2-s2.0-85154552706