Level I axillary dissection in patients with breast cancer and tumor-involved sentinel lymph node after NAC is not sufficient for adequate nodal staging

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F23%3AE0110324" target="_blank" >RIV/00843989:_____/23:E0110324 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/23:00133908 RIV/47813059:19510/23:A0000464 RIV/00209805:_____/23:00079219

Result on the web

<a href="https://turkjsurg.com/full-text-pdf/1889/eng" target="_blank" >https://turkjsurg.com/full-text-pdf/1889/eng</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.47717/turkjsurg.2023.5984" target="_blank" >10.47717/turkjsurg.2023.5984</a>

Result language

angličtina

Original language name

Level I axillary dissection in patients with breast cancer and tumor-involved sentinel lymph node after NAC is not sufficient for adequate nodal staging

Original language description

Objective: The purpose of the study was to investigate the oncological sufficiency of level I axillary dissection for adequate histological nodal staging (ypN) in patients with breast cancer and tumor-involved sentinel lymph node (SLN) after neoadjuvant chemotherapy (NAC). Material and Methods: A prospective multicentre pilot study took place from 01.01.2018 to 30.11.2020 in three mammary centres in the Czech Republic in patients with breast cancer after NAC (NCT03556397). Patients in the cohort with positive histological frozen section of SLN were indicated to separate axillary dissection of levels I and II. Results: Sixty-one patients with breast cancer after NAC were included in the study according to inclusion and exclusion criteria. Twelve patients with breast cancer and tumour involved SLN after NAC were further included in the analysis. Two (16.7%) patients had positive non-sentinel lymph nodes in level I only, one (8.3%) patient had positive lymph nodes in level II only, and seven (58.3%) patients had positive lymph nodes in both levels. Level I axillary dissection in a patient with tumour involved SLN after NAC would have resulted in understaging in five (41.7%) patients, mostly ypN1 instead of ypN2. Conclusion: According to our pilot result, level I axillary dissection is not sufficient in terms of adequate histological nodal staging in breast cancer patients after NAC, and level II axillary dissection should not be omitted.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30212 - Surgery

Project

—

Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Turkish journal of surgery

ISSN

2564-6850

e-ISSN

2564-7032

Volume of the periodical

39

Issue of the periodical within the volume

1

Country of publishing house

TR - TURKEY

Number of pages

6

Pages from-to

1-6

UT code for WoS article

000946256700003

EID of the result in the Scopus database

2-s2.0-85164974506