Hypertension in pediatric kidney transplantation

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F23%3AE0110331" target="_blank" >RIV/00843989:_____/23:E0110331 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11130/23:10462229 RIV/00064203:_____/23:10462229

Result on the web

<a href="https://onlinelibrary.wiley.com/doi/10.1111/petr.14522" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1111/petr.14522</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/petr.14522" target="_blank" >10.1111/petr.14522</a>

Result language

angličtina

Original language name

Hypertension in pediatric kidney transplantation

Original language description

Arterial hypertension (HTN) in children after kidney transplantation is an important risk factor not only for graft loss but also for cardiovascular morbidity and mortality. The prevalence of posttransplant HTN ranges between 60% and 90%. The etiology of posttransplant HTN is multifactorial and includes residual chronic native kidney disease, immunosuppressive therapy, and chronic allograft dysfunction among other causes. Clinic blood pressure (BP) should be measured at each outpatient visit. However, ambulatory blood pressure monitoring (ABPM) is the gold standard method for BP evaluation in children after kidney transplantation, as it often reveals masked and nocturnal HTN; given this, it should be regularly performed in each transplanted child. All classes of antihypertensive drugs are used in the treatment of posttransplant HTN because it has never been proven that one class is better than another. However, in several retrospective studies, the use of calcium channel blockers is associated with better graft function. The optimal target BP for transplanted children is still a matter of debate; it is recommended to target the same BP as for healthy children, that is, <95th percentile. Control of HTN in transplanted children remains poor – only 20%–50% of treated children have normal BP. There is a great potential for improvement of antihypertensive treatment that could potentially result in improvement of both graft and patient survival in children after kidney transplantation.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30209 - Paediatrics

Project

—

Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Pediatric transplantation

ISSN

1397-3142

e-ISSN

1399-3046

Volume of the periodical

27

Issue of the periodical within the volume

5

Country of publishing house

US - UNITED STATES

Number of pages

14

Pages from-to

1-14

UT code for WoS article

000975834800001

EID of the result in the Scopus database

2-s2.0-85156272714