Microbiota diversity in non-small cell lung cancer gut and mouth cavity microbiota diversity in non-small cell lung cancer patients

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F23%3AE0110580" target="_blank" >RIV/00843989:_____/23:E0110580 - isvavai.cz</a>

Alternative codes found

RIV/61988987:17110/23:A2402NCS RIV/61989100:27350/23:10253509 RIV/61989100:27640/23:10253509 RIV/00098892:_____/23:10158507 RIV/61989592:15110/23:73622108

Result on the web

<a href="https://sciendo.com/article/10.33073/pjm-2023-044" target="_blank" >https://sciendo.com/article/10.33073/pjm-2023-044</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.33073/pjm-2023-044" target="_blank" >10.33073/pjm-2023-044</a>

Result language

angličtina

Original language name

Microbiota diversity in non-small cell lung cancer gut and mouth cavity microbiota diversity in non-small cell lung cancer patients

Original language description

Lung malignancies have a substantial impact on cancer incidence and mortality worldwide. Even though many factors involved in the development of the disease are known, many questions remain unanswered. Previous studies suggest that the intestinal microbiota may have a role in developing malignant diseases. According to some findings, the microbiota has proven to be a key modulator of carcinogenic processes and the immune response against cancer cells, potentially influencing the effectiveness of immunotherapy. In our study, we characterized culturable microorganisms associated with non-small cell lung cancer (NSCLC) that can be recovered from rectal swabs and mouthwash. In addition, we also explored differences in the culturable microbiota with two main types of NSCLC - adenocarcinoma (ADC) and squamous cell carcinoma (SCC). With 141 patients included in the study (86 ADC and 55 SCC cases), a significant difference was observed between the two types in seven bacterial species (Collinsella, Corynebacterium, Klebsiella, Lactobacillus, Neisseria, Rothia, and Streptococcus), including the site of origin. The relationship between microbial dysbiosis and lung cancer is poorly understood; future research could shed light on the links between gut microbiota and lung cancer development.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30204 - Oncology

Project

<a href="/en/project/NV19-03-00069" target="_blank" >NV19-03-00069: Correlation of immunotherapeutic molecular targets with gut microbiome in NSCLC patients</a><br>

Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Polish journal of microbiology

ISSN

1733-1331

e-ISSN

2544-4646

Volume of the periodical

72

Issue of the periodical within the volume

4

Country of publishing house

PL - POLAND

Number of pages

9

Pages from-to

467-475

UT code for WoS article

001126091300002

EID of the result in the Scopus database

2-s2.0-85179898716