Mulberry posterior inferior nasal turbinate is associated with a lower pharyngeal pH environment
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F24%3AE0110601" target="_blank" >RIV/00843989:_____/24:E0110601 - isvavai.cz</a>
Alternative codes found
RIV/61988987:17110/24:A2502NEF RIV/61989100:27240/24:10252532
Result on the web
<a href="https://onlinelibrary.wiley.com/doi/10.1002/lary.30766" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1002/lary.30766</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/lary.30766" target="_blank" >10.1002/lary.30766</a>
Alternative languages
Result language
angličtina
Original language name
Mulberry posterior inferior nasal turbinate is associated with a lower pharyngeal pH environment
Original language description
Objectives: Mulberry-like changes of the posterior inferior nasal turbinate (MPINT) can lead to nasal obstruction. Extraesophageal reflux (EER) characterized by lower pH causes mucosal inflammation and therefore can contribute to sinonasal pathologies. No prior studies have objectively examined the possible association between acidic pH and MPINT formation. Therefore, this study is aimed to investigate the 24-h pharyngeal pH value in patients with MPINT. Study design: Prospective case-control multi-center study. Methods: Fifty-five patients with chronic EER symptoms were included in the study. They filled in questionnaires aimed at reflux and sinonasal symptoms (RSI®, SNOT-22) and underwent video endoscopy evaluating the laryngeal findings (RFS®) and the presence or absence of the MPINT. And, 24-h oropharyngeal pH monitoring was used to detect the acidic pH environment in the pharynx. Results: Out of the 55 analyzed patients, 38 had the MPINT (group 1), and in 17 patients, the MPINT was absent (group 2). Based on the pathological RYAN Score, in 29 (52.7%) patients, severe acidic pH drops were detected. In group 1, the acidic pH drops were diagnosed significantly more often (68.4%) compared with those in group 2 (p = 0.001). Moreover, in group 1, a significantly higher median total percentage of time spent below pH 5.5 (p = 0.005), as well as a higher median number of events lasting more than 5 min (p = 0.006), and higher median total number of events with pH drops (p = 0.017) were observed. Conclusion: In this study, the MPINT was significantly more often present in patients with acidic pH events detected by 24-h oropharyngeal pH monitoring. Acidic pH in the pharynx might lead to MPINT formation.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30206 - Otorhinolaryngology
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
The Laryngoscope
ISSN
0023-852X
e-ISSN
1531-4995
Volume of the periodical
134
Issue of the periodical within the volume
1
Country of publishing house
US - UNITED STATES
Number of pages
7
Pages from-to
62-68
UT code for WoS article
000996146900001
EID of the result in the Scopus database
2-s2.0-85160949237