Ambulatory isolated diastolic hypertension and risk of left ventricular hypertrophy in children with primary and secondary hypertension
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F24%3AE0111194" target="_blank" >RIV/00843989:_____/24:E0111194 - isvavai.cz</a>
Alternative codes found
RIV/61988987:17110/24:A2503AL2 RIV/00216208:11130/24:10482042
Result on the web
<a href="https://link.springer.com/article/10.1007/s00467-024-06457-8" target="_blank" >https://link.springer.com/article/10.1007/s00467-024-06457-8</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00467-024-06457-8" target="_blank" >10.1007/s00467-024-06457-8</a>
Alternative languages
Result language
angličtina
Original language name
Ambulatory isolated diastolic hypertension and risk of left ventricular hypertrophy in children with primary and secondary hypertension
Original language description
Background: Pediatric blood pressure (BP) assessment and management is increasingly important. Uncontrolled systolic and combined hypertension leads to hypertension-mediated organ damage. The impact of isolated diastolic hypertension is less clearly understood. Methods: We analyzed the prevalence of ambulatory isolated diastolic hypertension (IDH) in primary (PH) and secondary (SH) hypertension, and associations with BMI Z-score (BMIz) and left ventricular mass index adjusted to the 95th percentile (aLVMI) in a large, multicenter cohort of hypertensive children. Hypertensive children were divided and analyzed in three ambulatory hypertension subgroups: 24-h, daytime, and nighttime. Specifically, we sought to determine the prevalence of ambulatory 24-h, daytime, or nighttime IDH. Results: Prevalence of IDH varied based on ambulatory phenotypes, ranging from 6 to 12%, and was highest in children with SH. Children with IDH tended to be more likely female and, in some cases, were leaner than those with isolated systolic hypertension (ISH). Despite previous pediatric studies suggesting no strong association between diastolic blood pressure and left ventricular hypertrophy (LVH), we observed that children with IDH were equally likely to have LVH and had comparable aLVMI to those with ISH and combined systolic-diastolic hypertension. Conclusions: In summary, ambulatory IDH appears to be a unique phenotype with a female sex, and younger age predilection, but equal risk for LVH in children with either PH or SH.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30209 - Paediatrics
Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Pediatric nephrology
ISSN
0931-041X
e-ISSN
1432-198X
Volume of the periodical
39
Issue of the periodical within the volume
12
Country of publishing house
DE - GERMANY
Number of pages
9
Pages from-to
3533-3541
UT code for WoS article
001272648300003
EID of the result in the Scopus database
2-s2.0-85198952718