Risk factors and postoperative complications of lobectomy for non-small cell lung cancer: An exploratory analysis of premedication and clinical variables
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F24%3AE0111311" target="_blank" >RIV/00843989:_____/24:E0111311 - isvavai.cz</a>
Alternative codes found
RIV/61988987:17110/24:A2503A8T RIV/61989100:27240/24:10256930
Result on the web
<a href="https://www.mdpi.com/1648-9144/60/12/2088" target="_blank" >https://www.mdpi.com/1648-9144/60/12/2088</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/medicina60122088" target="_blank" >10.3390/medicina60122088</a>
Alternative languages
Result language
angličtina
Original language name
Risk factors and postoperative complications of lobectomy for non-small cell lung cancer: An exploratory analysis of premedication and clinical variables
Original language description
Background and Objectives: Postoperative pneumonia and complications significantly impact outcomes in thoracic surgery, particularly for patients undergoing lobectomy for non-small cell lung cancer (NSCLC). This study evaluates whether preoperative premedication influences the risk of postoperative pneumonia and overall complications. Materials and Methods: This retrospective study included 346 patients who underwent lobectomy for NSCLC at the University Hospital Ostrava between 2015 and 2021. Data on demographic variables, tumour staging, surgical approach, and premedication (anticholinergics, benzodiazepines, antihistamines, and analgesics) were analysed. Postoperative outcomes included pneumonia and complications classified by the modified Clavien–Dindo system. Results: Premedication was not significantly associated with postoperative pneumonia (10.7%) or overall complications (26.0%). Tumour size was the only factor significantly associated with complications, with larger tumours increasing the odds (OR: 1.16, p = 0.032). Other factors, including age, ASA classification, BMI, and surgical approach, did not demonstrate significant associations with postoperative outcomes. Conclusions: Premedication does not appear to significantly influence the risk of postoperative pneumonia or overall complications in patients undergoing lobectomy for NSCLC. Similarly, other clinical variables, such as age, ASA classification, BMI, and surgical approach, also did not show significant associations with these outcomes. These findings suggest that premedication can be individualised without increasing postoperative risks. However, tumour size emerged as a significant factor associated with complications, highlighting the need for careful preoperative assessment and planning, particularly in patients with larger tumours.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30212 - Surgery
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Medicina
ISSN
1010-660X
e-ISSN
1648-9144
Volume of the periodical
60
Issue of the periodical within the volume
12
Country of publishing house
CH - SWITZERLAND
Number of pages
12
Pages from-to
1-12
UT code for WoS article
001384914300001
EID of the result in the Scopus database
2-s2.0-85213445769