Prehabilitation during neoadjuvant therapy in patients with cancer of the upper gastrointestinal tract and rectum - the study protocol

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F25%3AE0111450" target="_blank" >RIV/00843989:_____/25:E0111450 - isvavai.cz</a>

Alternative codes found

RIV/61988987:17110/25:A2603D7R

Result on the web

<a href="https://www.frontiersin.org/journals/sports-and-active-living/articles/10.3389/fspor.2024.1495398/full?utm_source=F-NTF&utm_medium=EMLX&utm_campaign=PRD_FEOPS_20170000_ARTICLE" target="_blank" >https://www.frontiersin.org/journals/sports-and-active-living/articles/10.3389/fspor.2024.1495398/full?utm_source=F-NTF&utm_medium=EMLX&utm_campaign=PRD_FEOPS_20170000_ARTICLE</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3389/fspor.2024.1495398" target="_blank" >10.3389/fspor.2024.1495398</a>

Result language

angličtina

Original language name

Prehabilitation during neoadjuvant therapy in patients with cancer of the upper gastrointestinal tract and rectum - the study protocol

Original language description

Aims: The concept of prehabilitation, defined as interventions aimed at enhancing a patient's functional capacity prior to an impending physiological stressor, may contribute to reduced postoperative morbidity and mortality. The study's goal is to verify or refute the feasibility of a prehabilitation programme for two diagnostic patient groups during neoadjuvant chemo(radio)therapy, which is prescribed before the scheduled surgical procedure. This is a single group study design, with all patients enrolled receiving the intervention. Methods: This is an interventional feasibility study of a prehabilitation programme in the form of physical training conducted at home. The training consists of progressively dosed walking and strength exercises for selected muscle groups. Data will be monitored telemetrically and also through telephone contact with participants. Primary outcomes include: the percentage of patients interested in participating in the study out of all patients indicated for neoadjuvant therapy at University Hospital Ostrava during the observed period, the percentage of patients who complete the prehabilitation programme until the date of surgery and individual patient compliance. Secondary outcomes include physical fitness parameters obtained from cardiopulmonary exercise testing, grip strength measured by a dynamometer, changes in body composition, EORTC QLQ-C30 quality of life questionnaire, and a questionnaire on the subjective perception of the exercise programme. Both primary and secondary outcomes will be compared between study arms (two diagnostic groups). The study is registered at ClinicalTrials.gov, ID: NCT05646043. Conclusion: The results of this study can serve as a foundation for larger, multicentre, controlled studies in the future.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30306 - Sport and fitness sciences

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2025

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Frontiers in sports and active living

ISSN

2624-9367

e-ISSN

2624-9367

Volume of the periodical

6

Issue of the periodical within the volume

article 1495398

Country of publishing house

CH - SWITZERLAND

Number of pages

7

Pages from-to

1-7

UT code for WoS article

001423188000001

EID of the result in the Scopus database

2-s2.0-85219419489