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Extracorporeal blood purification in European pediatric intensive care units: a consensus statement

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F25%3AE0111500" target="_blank" >RIV/00843989:_____/25:E0111500 - isvavai.cz</a>

  • Result on the web

    <a href="https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2829833" target="_blank" >https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2829833</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1001/jamanetworkopen.2024.57657" target="_blank" >10.1001/jamanetworkopen.2024.57657</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Extracorporeal blood purification in European pediatric intensive care units: a consensus statement

  • Original language description

    Importance: Important advances have been made in extracorporeal blood purification therapies (EBPTs) due to new technologies and biomaterials; however, the lack of established guidelines is a factor in great variability in clinical practice. This aspect is accentuated in pediatric intensive care given the small number of patients with diverse diagnoses treated with EBPT and the technical challenges in treating small children, potentiating the risk of adverse events. Objective: To understand what experienced users of EBPT think about its relevant issues, insight that may have implications for the design of future studies, and the application of EBPTs in patient care. Evidence review: Literature search was conducted using the PubMed and Embase databases between January 1, 2020, and July 15, 2024, and a combination of key medical terms. A panel of experts was formed (composed of 15 authors and pediatric intensivists) to develop a consensus statement using a modified Delphi-based model between 2022 and 2024. The panel's core team drafted the initial questionnaire, which explored EBPT use in pediatric intensive care units (PICUs), including clinical indications for initiating and discontinuing use and outcomes for assessing effectiveness and safety. SurveyMonkey was used in the distribution, completion, and revision of the questionnaire, and findings were analyzed. Panelists were asked to rank answer choices. Numerical value for each ranking was translated to a percentage defining the strength of consensus (>90% agreement from panelists signifying strong consensus; <49% signifying no consensus). Findings: A total of 116 survey responses were received from panelists from 8 European countries. Strong consensus was achieved on 6 of 24 questions and consensus (75%-90% agreement) was reached on 18 of 24 questions. According to the panelists, the continuous renal replacement therapy standard or enhanced adsorption hemofilter and plasma exchange were of interest, representin...

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30209 - Paediatrics

Result continuities

  • Project

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2025

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    JAMA Network Open

  • ISSN

    2574-3805

  • e-ISSN

    2574-3805

  • Volume of the periodical

    8

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    16

  • Pages from-to

    1-16

  • UT code for WoS article

    001416055100008

  • EID of the result in the Scopus database

    2-s2.0-85217832246