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Impact of COVID-19 on kidney transplant outcomes: An 8-year study from the Czech Republic

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F25%3AE0112101" target="_blank" >RIV/00843989:_____/25:E0112101 - isvavai.cz</a>

  • Alternative codes found

    RIV/61988987:17110/25:A2603CKT RIV/61989100:27240/25:10260021

  • Result on the web

    <a href="https://annalsoftransplantation.com/abstract/index/idArt/950961" target="_blank" >https://annalsoftransplantation.com/abstract/index/idArt/950961</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.12659/AOT.950961" target="_blank" >10.12659/AOT.950961</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Impact of COVID-19 on kidney transplant outcomes: An 8-year study from the Czech Republic

  • Original language description

    BACKGROUND: The Coronavirus disease 2019 (COVID-19) pandemic disrupted transplant programs worldwide. Transplant recipients are especially vulnerable to the effects of SARS-CoV-2 infection due to immunosuppression. This study assessed the impact of the COVID-19 pandemic on kidney transplant outcomes. MATERIAL AND METHODS: We performed a single-center, retrospective cohort study of the kidney transplant program in the Czech Republic. The analysis included 145 recipients transplanted from 138 donors between 2015 and 2022. Cohorts were defined by donor procurement before the pandemic (n=94) or during the pandemic (n=44). The analysis focused on short- and long-term graft and patient outcomes of both groups. RESULTS: No significant differences were found in postoperative kidney graft function (P=0.160) or overall survival before and during the pandemic. The 1- and 3-year survival rates before the pandemic were 96.0% and 90.9%. During the pandemic, they were 97.8% at both time points (P=0.092). Deathcensored failure-free survival was 95.9% and 90.4% at 1 and 3 years before the pandemic versus 95.6% at 1 and 3 years during the pandemic, respectively (P=0.377). Estimated glomerular filtration rate at 7 days (P=0.233) and 1 month (P=0.893) did not differ between vaccinated and non-vaccinated recipients. CONCLUSIONS: The COVID-19 pandemic had no significant impact on the short- or long-term outcomes of the kidney transplantation program. These data support sustaining standard kidney transplantation programs during health crises.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30213 - Transplantation

Result continuities

  • Project

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2025

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Annals of transplantation

  • ISSN

    1425-9524

  • e-ISSN

    2329-0358

  • Volume of the periodical

    30

  • Issue of the periodical within the volume

    article e950961

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    9

  • Pages from-to

    1-9

  • UT code for WoS article

    001654564300001

  • EID of the result in the Scopus database

    2-s2.0-105026323716