Options of genetic testing and methylation analysis of circulating free tumor DNA (tumor cell-free DNA) isolated from peripheral blood of NSCLC patients

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F26475821%3A_____%2F12%3A%230000115" target="_blank" >RIV/26475821:_____/12:#0000115 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Options of genetic testing and methylation analysis of circulating free tumor DNA (tumor cell-free DNA) isolated from peripheral blood of NSCLC patients

Original language description

The results of our pilot study demonstrate the potential use of free DNA in the peripheral blood not only to investigate the presence of EGFR mutations and KRAS gene but also for the examination metylation status of genes important for the biological behavior of non-small cell carcinoma. EGFR mutations and KRAS were used in this study as a marker of the presence of tumor DNA in peripheral blood.

Czech name

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Czech description

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Type

A - Audiovisual production

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

<a href="/en/project/NS9718" target="_blank" >NS9718: New possibilities for application of molecular-diagnostic methods for early detection and proper therapy selection of progressing Non-Small Cell Lung Cancer based on detection and monitoring of hypermethylation of specific genes</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

ISBN

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Place of publication

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Publisher/client name

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